BIOMO202-20B (HAM)

Genetics

15 Points

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Division of Health Engineering Computing & Science
School of Science
Biomedical, Molecular and Cellular Biology

Staff

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: cheryl.ward@waikato.ac.nz

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Paper Description

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This paper deals with genetics in the widest sense from the molecular and cellular to the applied and evolutionary. Both prokaryote and eukaryote genetics are discussed with respect to DNA replication, hereditary, gene expression and control, and the role of mutations at both the DNA and chromosomal levels. The paper provides a pathway from basic research in molecular genetics to clinical applications in health and disease.

The paper is seen as being of importance to students of biology, irrespective of whether their interests are in metabolic and cellular processes, plant/animal genetic improvement, or ecological and evolutionary. This paper is required for the Molecular and Cellular Biology major.

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Paper Structure

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A traditional lecture paper supplemented by weekly tutorials with five laboratory sessions (one computer and four lab sessions). You will be required to assign yourself to one lab stream (Thursday or Friday). You can use the attendance button on Moodle to keep up-to-date with the timetable.

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Learning Outcomes

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Students who successfully complete the paper should be able to:

  • Describe how chromosomes are packaged and the process of gene expression and its regulation in cells.
    Linked to the following assessments:
  • Explain the principles of Mendelian and non‐Mendelian inheritance.
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  • Describe the genetics of mammalian and bacterial genomes
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  • Explain gene variation and frequency in populations
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  • Describe the genetics of cancer and the immune system
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  • Describe the history and mechanism of CRISPR
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  • Perform a range of practical laboratory techniques, including bacterial transformation, DNA extraction, PCR, gel electrophoresis, and experimental design and analysis.
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Assessment

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The dates indicated for assessment procedures will normally be adhered to. Any changes to the dates will be made in consultation with the class at least one week prior to the original date. Satisfactory completion of the laboratory sessions and tests are also an essential element of the paper and irrespective of the marks you receive must be completed in order to pass the paper. Medical certificates must be presented for any test and laboratory missed.

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Assessment Components

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The internal assessment/exam ratio (as stated in the University Calendar) is 100:0. There is no final exam. The final exam makes up 0% of the overall mark.

The internal assessment/exam ratio (as stated in the University Calendar) is 100:0 or 0:0, whichever is more favourable for the student. The final exam makes up either 0% or 0% of the overall mark.

Component DescriptionDue Date TimePercentage of overall markSubmission MethodCompulsory
1. Online Theory Test 1
13 Aug 2020
9:00 AM
10
  • Online: Submit through Moodle
2. Online Theory Test 2
5 Oct 2020
10:00 AM
10
  • Hand-in: In Tutorial
  • Online: Submit through Moodle
3. Online Moodle quizzes
10
  • Online: Submit through Moodle
4. Bacterial Genetics Practical Written Laboratory Report
21 Aug 2020
4:30 PM
10
  • Online: Submit through Moodle
5. Bacterial Genetics Practical - Group Oral Poster Presentation
14 Oct 2020
4:30 PM
20
  • In Class: In Lab
  • Online: Submit through Moodle
6. Final Online 2 hr Theory Test III
40
Assessment Total:     100    
Failing to complete a compulsory assessment component of a paper will result in an IC grade
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Required and Recommended Readings

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Required Readings

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"Genetics: From Genes to Genomes" 6th Ed, Hartwell et al. (McGraw-Hill, 2018)

Relevant chapters (Ch) from this book are listed for each lecture in the schedule.

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Recommended Readings

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Refer to the Moodle Topics for additional supplementary readings.
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Other Resources

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See Moodle page for information regarding Studiosity. This in an opportunity to review study help and connect in real-time with live experts or get Writing Feedback in less than 24 hours.
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Online Support

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This paper has a Moodle page (http://elearn.waikato.ac.nz) where you will be able to access pdfs of lecture notes and powerpoints, lecture recordings, and assessment materials. There are also discussion forums where you can both ask and answer questions.

PLEASE NOTE: Moodle will be used for class notices and it is your responsibility to check the site regularly. Instructions provided on Moodle and in lectures are considered to be given to the class as a whole.

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Workload

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Approximately 70 contact hours, constituting lectures (24) plus laboratories (5), moodle quizzes, tutorials (10), theory tests (2), and poster presentation (1). A student would be expected to spend an equal time on study and assessment during the year.

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Linkages to Other Papers

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This paper is relevant to those undertaking Molecular and Biology papers such as Biochemistry (BIOMO201), Microbiology (BIOMO203), and Physiology (BIOMO204). In addition, to students with majors/minors in Ecology and Biodiversity and/or Environmental Science.

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Prerequisite(s)

Prerequisite papers: BIOMO101 or BIOL101

Corequisite(s)

Equivalent(s)

Restriction(s)

Restricted papers: BIOL210

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