This paper is targeted at students interested in biochemistry, plant and animal physiology, biotechnology, genetics, microbiology and chemistry. We will build on the principles of biochemistry introduced in BIOMO201 to consider metabolic regulation through the molecular control of enzyme activity and cellular communication, including the trafficking of proteins between organelles, cellular stress responses and cell-death, as well as human diseases (e.g. diabetes). We will also examine how protein structures are determined, the process of nucleotide metabolism and transcription and features of molecular motors (such as the ATP synthase). Students will also be required to evaluate and submit a written report on recent findings in Biochemistry and Molecular cell biology.

This paper will be taught with a blended learning style. Material will be provided on the Moodle page for discussion at timetabled tutorial sessions. Tutorial sessions may be attended in person or via Zoom. Assessments are in the form of a written assignment, online tests/exam and six practical sessions.

Practical classes:

Practical classes will run in weeks 3-6 and weeks 10-11 (27th July to 22nd September)

Labs will be run in R.1.20 for practicals 1-5, and GB.13 for practical 6. Sessions are run Mon 2.00-5.00 pm and Tue 2.00-5.00 pm. You should attend one of these sessions. A sign up form for the lab streams will be posted on the course Moodle site.

The practical work is designed to give experience in learning, from published methods and manufacturers' instructions, a range of techniques commonly used in modern biochemistry laboratories.

NOTE If you are not able to attend the scheduled labs during the semester, we will be running a 3 day lab block during trimester C (dates and details will be posted on the course Moodle site). As this will be a condensed version of the cell labs 1-4, there will be additional assessment tasks relating to the cell labs (such as an assignment and or oral presentations). Labs 5 and 6 will be a replication from the scheduled labs run during trimester B.

You should note that the practical classes are an integral part of the course.

20% on the written report, 20% on the laboratory course, 30% on two tests and 30% on final assessment (either an exam or assignment)

The two tests will be held in the usual tutorial time on line via Moodle on 6th of August and 1st October.

Due dates for the written reports are shown on the timetable attached to this outline. These reports will need to be submitted on line via the course Moodle site and will be subjected to Turnitin software check. Lateness in handing in reports will be penalised by loss of 10% of the mark per working day.

Any queries related to assessment should be directed to Dr. Ryan Martinus.

This paper has a Moodle page (http://elearn.waikato.ac.nz) where you will be able to access pdfs of lecture notes and powerpoints, lecture recordings, and assessment materials. There are also discussion forums where you can both ask and answer questions.

PLEASE NOTE: Moodle will be used for class notices etc and it is your responsibility to check the site regularly. Instructions provided on Moodle and in lectures are considered to be given to the class as a whole.

Lectures/tutorials : 22 hours contact, Laboratory classes 18 hours contact, Assessment: ( 2 Tests on line, Research paper review 6 hours, Examination on line).