BIOMO302-19A (HAM)

Advanced Genetics

15 Points

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Division of Health Engineering Computing & Science
School of Science

Staff

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Convenor(s)

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: cheryl.ward@waikato.ac.nz

You can contact staff by:

  • Calling +64 7 838 4466 select option 1, then enter the extension.
  • Extensions starting with 4, 5, 9 or 3 can also be direct dialled:
    • For extensions starting with 4: dial +64 7 838 extension.
    • For extensions starting with 5: dial +64 7 858 extension.
    • For extensions starting with 9: dial +64 7 837 extension.
    • For extensions starting with 3: dial +64 7 2620 + the last 3 digits of the extension e.g. 3123 = +64 7 262 0123.
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Paper Description

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This paper follows on from BIOMO202-18B and deals in greater details with bacterial and mammalian genomes, molecular events within the cell, the expression of genes, genetic variation, inheritance, human disease, complex traits, genetic analyses and population genetics. This paper is recommended to all biologists; it complements ecological, physiology and biochemical studies and aims to illustrate how genes interact in genomes, organisms, populations and human disease.
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Paper Structure

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BIOMO302 is a traditional lecture course supplemented by six laboratories. All lectures will be recorded by Panopto.

Attendance in all lectures and labs will be monitored.

Important note for international students: For international students in New Zealand under student visas, regular attendance is part of your visa obligation and is checked as a requirement on the University under the Code of Practice for the Pastoral Care of International Students, to which the University is a signatory. Academic staff are formally required to monitor attendance in classes and submission of compulsory assessment events/items and to report to Waikato International in the event that any problem with irregular attendance or non-submission is not resolved.

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Learning Outcomes

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Students who successfully complete the course should be able to:

  • Perform a range of practical laboratory techniques, including DNA and RNA extraction, cDNA preparation, real-time PCR, gel electrophoresis, and experimental design and analysis.
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  • To describe the general architecture of a mammalian genome
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  • To explain how DNA is packaged and its influence on gene expression
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  • To understand the molecular technologies involved in DNA sequencing
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  • To explain how microbial chromosomes are replicated
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  • To describe the replication of viruses in their host cells
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  • To discuss the major causes of human genetic diversity
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  • To describe the various classes of genetic disease
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  • To explain gene variation and frequency in populations
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  • To discuss the genetic basis of cancer
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  • To distinguish between the three types of stem cells
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  • To explain the potential influence of genetic discovery and technologies in medicine
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  • To describe the role of evolution in the development of various protein domains
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Assessment

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The dates indicated for assessment procedures will normally be adhered to. Any changes to the dates will be made in consultation with the class at least one week prior to the original date. Attendance of the laboratory sessions are an essential element of the course and must be completed in order to pass the course. Medical certificates must be presented for any test and/or laboratory missed.
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Assessment Components

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The internal assessment/exam ratio (as stated in the University Calendar) is 50:50. There is no final exam. The final exam makes up 50% of the overall mark.

The internal assessment/exam ratio (as stated in the University Calendar) is 50:50 or 0:0, whichever is more favourable for the student. The final exam makes up either 50% or 0% of the overall mark.

Component DescriptionDue Date TimePercentage of overall markSubmission MethodCompulsory
1. Lecture Test I
18 Mar 2019
10:00 AM
10
  • Hand-in: In Lecture
2. Lecture Test II
2 May 2019
2:00 PM
10
  • Hand-in: In Lecture
3. Gene Expression Laboratory Report
29 Apr 2019
4:30 PM
10
  • Hand-in: Faculty Information (FG Link)
4. Lecture Test III
23 May 2019
2:00 PM
10
  • Hand-in: In Lecture
5. Laboratory Manual on Population Genetics
27 May 2019
4:30 PM
10
  • Hand-in: Faculty Information (FG Link)
6. Exam
50
Assessment Total:     100    
Failing to complete a compulsory assessment component of a paper will result in an IC grade
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Required and Recommended Readings

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Required Readings

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Genetics: From genes to Genomes, Hartwell, L. H. et al., 6th Ed, 2018 (McGraw Hill)
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Other Resources

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Online Support

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This paper has a Moodle page (http://elearn.waikato.ac.nz) where you will be able to access pdfs of lecture notes and powerpoints, lecture recordings, and assessment materials. There are also discussion forums where you can both ask and answer questions.

PLEASE NOTE: Moodle will be used for class notices etc and it is your responsibility to check the site regularly. Instructions provided on Moodle and in lectures are considered to be given to the class as a whole.


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Workload

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Approximately 53 contact hours, constituting lectures plus laboratories. A student would be expected to spend an equal time on study and assessment during the year.


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Linkages to Other Papers

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BIOMO301 - Advanced Biochemistry

BIOMO303 - Advanced Microbiology

BIOMO304 - Applied Animal Physiology

BIOMO306 - Molecular Biology and Health

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Prerequisite(s)

Prerequisite papers: BIOMO202 or BIOMO204 or BIOL210

Corequisite(s)

Equivalent(s)

Restriction(s)

Restricted papers: BIOL310

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