BIOMO501-21B (HAM)

Biomolecular Structure and Cellular Pathways

15 Points

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Division of Health Engineering Computing & Science
School of Science
Biomedical, Molecular and Cellular Biology

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: cheryl.ward@waikato.ac.nz

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Paper Description

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This paper will equip students with a working understanding of advanced techniques used in biochemical research to probe the structure, interactions and biological functions of proteins from the molecular to the organism level. Topics will include bioinformatic methods of proteins analysis, in vitro and in vivo characterization, structure determination and protein engineering. Students will engage in active learning to gain information about various methods used in biochemical research, and then apply these methods to a biochemical system of their choice through a series of guided workshops. They will then synthesize this knowledge to design a research program and write a proposal.

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Paper Structure

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The paper will comprise ten 2 hr tutorials and workshops, each of which will contribute 5% of the course mark (50% total). Throughout the course, students will work towards designing a research program focused on investigating a protein of their choice, which would implement the techniques discussed in tutorials. A written research proposal outlining their program will be submitted for assessment at the end of the course (40%) and presented in a final oral seminar (10%).

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Learning Outcomes

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Students who successfully complete the paper should be able to:

  • - Compare the strengths and limitations of different biochemical methods and how they can be applied to research questions
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  • - Evaluate the use of different analysis methods in literature examples and judge whether they are appropriate
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  • - Design an original set of analyses to investigate the biochemical properties of proteins
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  • - Develop a research strategy to answer biochemical questions in a wider societal context
    Linked to the following assessments:
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Assessment

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Course work: final exam ratio is 100:0

Course work consists of completing a written research proposal on a particular topic (40% of final course mark) and pitching this proposal in a short seminar (10% of final course mark).

The remaining 50% of the final course mark will be based on seminar presentations during in-class discussions and completion of tasks during workshops.

Assessment Components

The internal assessment/exam ratio (as stated in the University Calendar) is 100:0. There is no final exam.

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Assessment Components

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The internal assessment/exam ratio (as stated in the University Calendar) is 100:0. There is no final exam. The final exam makes up 0% of the overall mark.

The internal assessment/exam ratio (as stated in the University Calendar) is 100:0 or 0:0, whichever is more favourable for the student. The final exam makes up either 0% or 0% of the overall mark.

Component DescriptionDue Date TimePercentage of overall markSubmission MethodCompulsory
1. Seminar presentations and workshop tasks
50
  • In Class: In Tutorial
2. Research proposal
22 Oct 2021
12:00 AM
40
  • Online: Submit through Moodle
3. Presentation of proposal
10
  • Presentation: In Class
Assessment Total:     100    
Failing to complete a compulsory assessment component of a paper will result in an IC grade
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Required and Recommended Readings

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Required Readings

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Required reading will be supplied usually in the form of pdfs of required articles.
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Online Support

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This paper has a Moodle page (http://elearn.waikato.ac.nz) where you will be able to access pdfs of lecture notes and powerpoints, lecture recordings, and assessment materials. There are also discussion forums where you can both ask and answer questions.

PLEASE NOTE: Moodle will be used for class notices etc and it is your responsibility to check the site regularly. Instructions provided on Moodle and in lectures are considered to be given to the class as a whole.
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Workload

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Tutorials and workshops (12 hours contact). In addition, students are expected to spend one full day preparing for each tutorial/workshop which will include reading material and/or preparing presentations.

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Linkages to Other Papers

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Prerequisite(s)

Prerequisites: BIOL351 or BIOMO301

Corequisite(s)

Equivalent(s)

Restriction(s)

Restricted papers: BIOL582 and BIOL583

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